Mission Bay Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Mission Bay

Price found within the past 48 hours. Click for updated prices.
The Grove Inn
The Westin St. Francis San Francisco on Union Square
Beacon Grand, A Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf
DoubleTree by Hilton Hotel Berkeley Marina

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay

Mission Bay Hotel Deals

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $324 per night from Jul 17 to Jul 18
CA $324
CA $381 total
Jul 17 - Jul 18
includes taxes & fees
9.6/10 Exceptional! (2,514 reviews)
"Very friendly staff. Great location"

Reviewed on Jun 21, 2026

LUMA Hotel San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $282 per night from Jul 12 to Jul 13
CA $282
CA $397 total
Jul 12 - Jul 13
includes taxes & fees
9.2/10 Wonderful! (2,303 reviews)
"A"

Reviewed on Jun 21, 2026

Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is CA $198 per night from Jul 5 to Jul 6
CA $198
CA $234 total
Jul 5 - Jul 6
includes taxes & fees
9/10 Wonderful! (5,884 reviews)
"My family and I had a good time staying there"

Reviewed on Jun 21, 2026

Holiday Inn Golden Gateway by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay vacation package cost?
Custom make your Mission Bay vacation package from as low as CA $1,432. Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay vacation package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay vacation?
Smart travelers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organizing an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia vacation package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay vacation package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Discover the most popular places to visit in Mission Bay

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.