Mission Bay Vacation Packages
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Top Holiday Package Deals in Mission Bay
Price found within the past 48 hours. Click for updated prices.
The Westin St. Francis San Francisco on Union Square
Union Square
CA $1,364
per person
Nov 27 - Dec 4
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to San Francisco (SFO)
8.8/10 Excellent! (2,247 reviews)
Such a beautiful hotel in a prime location!
Reviewed on Sep 24, 2026
Where to stay in Mission Bay
Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Fisherman's Wharf
1 out of top 10 points of interest in this area
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco
3 out of top 10 points of interest in this area
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Mission Bay Hotel Deals
LUMA Hotel San Francisco
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
CA $346
CA $408 total
Oct 2 - Oct 3
includes taxes & fees
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
CA $215
CA $253 total
Oct 25 - Oct 26
includes taxes & fees
9/10 Wonderful! (6,331 reviews)
"Nice view"
Reviewed on Sep 25, 2026
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
CA $181
CA $272 total
Oct 18 - Oct 19
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Mission Bay vacation package cost?
Custom make your Mission Bay vacation package from as low as CA $1,114. Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay vacation package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay vacation?
Smart travelers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organizing an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia vacation package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay vacation package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
Stay near popular Mission Bay attractions
Chase Center
8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
Mission Bay Conference Center at UCSF
Learn about the events happening at Mission Bay Conference Center at UCSF during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its acclaimed art scene.
PIER 48 - Lot #39
After visiting PIER 48 - Lot #39, make a plan to see the other sights and activities in San Francisco. Amble around this vibrant area's Chinatown, or seek out the local tours.
Lefty O'Doul Bridge
You can find out about the history of San Francisco with a trip to Lefty O'Doul Bridge. Take in the acclaimed theater scene and beautiful sunsets in this vibrant area.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.